Pharmaceuticals (PPCPs)

 Pharmaceuticals and Personal Care Products (PPCPs)

Over the last decade the use of Pharmaceuticals and Personal Care Products (PPCPs) has doubled in the United States. As a result, PPCPs have entered the environment through both human activity and as by-products from manufacturing, agricultural activities, medical use and veterinarian facilities. PPCPs are usually introduced into the environment through the disposal of unused medications into sewer systems and trash. PPCPs tend to be water soluble and do not evaporate under normal temperatures, which is why they end up in soil and water. The full effects of PPCPs on the environment are not fully understood and there is concern about the potential threat they pose to the food chain. Because of the high solubility of most PPCPs, aquatic organisms are most vulnerable. The classes of pharmaceuticals found in these organisms have been linked to slow growth in frogs and the increased feminization of exposed fish. The scope of human exposure to PPCPs from the environment is complicated and increased monitoring is occurring to determine the effect on humans of long-term, low-level exposure to PPCPs.


Due to their persistent nature and toxicity, monitoring water sources for PPCPs is a growing priority for both government agencies and consumers. The following procedure outlines the fully automated, sample-to-vial extraction and concentration of water matrices for the detection of these compounds in one rapid and efficient process.


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